E848-2254 Screening compound: N-[(5-methylfuran-2-yl)methyl]-4-[5-(pyrrolidine-1-sulfonyl)-1H-indol-1-yl]butanamide

E848-2254 Screening compound: N-[(5-methylfuran-2-yl)methyl]-4-[5-(pyrrolidine-1-sulfonyl)-1H-indol-1-yl]butanamide
E848-2254 Screening compound: N-[(5-methylfuran-2-yl)methyl]-4-[5-(pyrrolidine-1-sulfonyl)-1H-indol-1-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E848-2254
N-[(5-methylfuran-2-yl)methyl]-4-[5-(pyrrolidine-1-sulfonyl)-1H-indol-1-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E848-2254

Molecular Formula

C22H27N3O4S (C22 H27 N3 O4 S)

Compound Name

N-[(5-methylfuran-2-yl)methyl]-4-[5-(pyrrolidine-1-sulfonyl)-1H-indol-1-yl]butanamide

IUPAC name

N-[(5-methylfuran-2-yl)methyl]-4-[5-(pyrrolidine-1-sulfonyl)-1H-indol-1-yl]butanamide

SMILES

Cc1ccc(CNC(CCCn(cc2)c(cc3)c2cc3S(N2CCCC2)(=O)=O)=O)o1

InChI

InChI=1S/C22H27N3O4S/c1-17-6-7-19(29-17)16-23-22(26)5-4-11-24-14-10-18-15-20(8-9-21(18)24)30(27,28)25-12-2-3-13-25/h6-10,14-15H,2-5,11-13,16H2,1H3,(H,23,26)

InChI Key

DYCDHMJGTLGJCY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14921496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.833

Distribution Coefficient, logD

2.833

Water Solubility, LogSw

-3.42

Polar Surface Area

65.867

Acid Dissociation Constant (pKa)

11.88

Base Dissociation Constant (pKb)

-0.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

E848-2254 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with E848-2254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E848-2254?
Check Price and Availability of E848-2254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E848-2254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E848-2254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E848-2254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E848-2254 available by request