E853-2434 Screening compound: ethyl 6-(benzylcarbamoyl)-6-methyl-5-[(5-methylfuran-2-yl)methyl]-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate

E853-2434 Screening compound: ethyl 6-(benzylcarbamoyl)-6-methyl-5-[(5-methylfuran-2-yl)methyl]-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate
E853-2434 Screening compound: ethyl 6-(benzylcarbamoyl)-6-methyl-5-[(5-methylfuran-2-yl)methyl]-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E853-2434
ethyl 6-(benzylcarbamoyl)-6-methyl-5-[(5-methylfuran-2-yl)methyl]-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E853-2434

Molecular Formula

C24H26N4O5 (C24 H26 N4 O5)

Compound Name

ethyl 6-(benzylcarbamoyl)-6-methyl-5-[(5-methylfuran-2-yl)methyl]-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate

IUPAC name

ethyl 6-(benzylcarbamoyl)-6-methyl-5-[(5-methylfuran-2-yl)methyl]-4-oxo-4H5H6H7H-pyrazolo[15-a]pyrazine-2-carboxylate

SMILES

CCOC(c1nn(CC(C)(C(NCc2ccccc2)=O)N(Cc2ccc(C)o2)C2=O)c2c1)=O

InChI

InChI=1S/C24H26N4O5/c1-4-32-22(30)19-12-20-21(29)27(14-18-11-10-16(2)33-18)24(3,15-28(20)26-19)23(31)25-13-17-8-6-5-7-9-17/h5-12H,4,13-15H2,1-3H3,(H,25,31)/t24-/m0/s1

InChI Key

AUPZRDUXYDYPHL-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD14922551

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.744

Distribution Coefficient, logD

2.744

Water Solubility, LogSw

-3.03

Polar Surface Area

81.761

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

-1.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

E853-2434 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E853-2434 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E853-2434?
Check Price and Availability of E853-2434, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E853-2434 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E853-2434
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E853-2434
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E853-2434 available by request