E865-0254 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide

E865-0254 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide
E865-0254 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E865-0254
N-[2-(4-chlorophenyl)ethyl]-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E865-0254

Molecular Formula

C28H26ClN3O3 (C28 H26 ClN3 O3)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H2H3H4H-pyrrolo[34-b]indol-2-yl]acetamide

SMILES

Cn1c(C(N(CC(NCCc(cc2)ccc2Cl)=O)C2c(cc3)ccc3OC)=O)c2c2c1cccc2

InChI

InChI=1S/C28H26ClN3O3/c1-31-23-6-4-3-5-22(23)25-26(19-9-13-21(35-2)14-10-19)32(28(34)27(25)31)17-24(33)30-16-15-18-7-11-20(29)12-8-18/h3-14,26H,15-17H2,1-2H3,(H,30,33)/t26-/m1/s1

InChI Key

ZJVCUMGUMRFXTR-AREMUKBSSA-N

MDL Number (MFCD)

MFCD14924479

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.99

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.434

Distribution Coefficient, logD

4.434

Water Solubility, LogSw

-4.85

Polar Surface Area

49.797

Acid Dissociation Constant (pKa)

14.61

Base Dissociation Constant (pKb)

0.41

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.40

E865-0254 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with E865-0254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E865-0254?
Check Price and Availability of E865-0254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E865-0254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E865-0254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E865-0254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E865-0254 available by request