E865-0292 Screening compound: N-cyclopropyl-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide

E865-0292 Screening compound: N-cyclopropyl-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide
E865-0292 Screening compound: N-cyclopropyl-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E865-0292
N-cyclopropyl-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E865-0292

Molecular Formula

C23H23N3O3 (C23 H23 N3 O3)

Compound Name

N-cyclopropyl-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H,2H,3H,4H-pyrrolo[3,4-b]indol-2-yl]acetamide

IUPAC name

N-cyclopropyl-2-[1-(4-methoxyphenyl)-4-methyl-3-oxo-1H2H3H4H-pyrrolo[34-b]indol-2-yl]acetamide

SMILES

Cn1c(C(N(CC(NC2CC2)=O)C2c(cc3)ccc3OC)=O)c2c2c1cccc2

InChI

InChI=1S/C23H23N3O3/c1-25-18-6-4-3-5-17(18)20-21(14-7-11-16(29-2)12-8-14)26(23(28)22(20)25)13-19(27)24-15-9-10-15/h3-8,11-12,15,21H,9-10,13H2,1-2H3,(H,24,27)/t21-/m0/s1

InChI Key

OQXPDVKSRGSNQB-NRFANRHFSA-N

MDL Number (MFCD)

MFCD14924496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.957

Distribution Coefficient, logD

2.957

Water Solubility, LogSw

-3.26

Polar Surface Area

50.012

Acid Dissociation Constant (pKa)

13.88

Base Dissociation Constant (pKb)

2.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

E865-0292 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E865-0292 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E865-0292?
Check Price and Availability of E865-0292, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E865-0292 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E865-0292
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E865-0292
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E865-0292 available by request