E882-1225 Screening compound: 1-[3-(4-bromophenyl)-1H-pyrazole-5-carbonyl]-4-cyclohexanecarbonylpiperazine

E882-1225 Screening compound: 1-[3-(4-bromophenyl)-1H-pyrazole-5-carbonyl]-4-cyclohexanecarbonylpiperazine
E882-1225 Screening compound: 1-[3-(4-bromophenyl)-1H-pyrazole-5-carbonyl]-4-cyclohexanecarbonylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E882-1225
1-[3-(4-bromophenyl)-1H-pyrazole-5-carbonyl]-4-cyclohexanecarbonylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E882-1225

Molecular Formula

C21H25BrN4O2 (C21 H25 BrN4 O2)

Compound Name

1-[3-(4-bromophenyl)-1H-pyrazole-5-carbonyl]-4-cyclohexanecarbonylpiperazine

IUPAC name

1-[3-(4-bromophenyl)-1H-pyrazole-5-carbonyl]-4-cyclohexanecarbonylpiperazine

SMILES

O=C(C1CCCCC1)N(CC1)CCN1C(c1cc(-c(cc2)ccc2Br)n[nH]1)=O

InChI

InChI=1S/C21H25BrN4O2/c22-17-8-6-15(7-9-17)18-14-19(24-23-18)21(28)26-12-10-25(11-13-26)20(27)16-4-2-1-3-5-16/h6-9,14,16H,1-5,10-13H2,(H,23,24)

InChI Key

CACPQIDUJCQZHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14925645

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.36

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.326

Distribution Coefficient, logD

4.325

Water Solubility, LogSw

-4.18

Polar Surface Area

56.025

Acid Dissociation Constant (pKa)

10.31

Base Dissociation Constant (pKb)

0.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

E882-1225 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E882-1225 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E882-1225?
Check Price and Availability of E882-1225, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E882-1225 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E882-1225
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E882-1225
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E882-1225 available by request