E897-0272 Screening compound: N-(3-chlorophenyl)-2-{2,4'-dioxo-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}acetamide

E897-0272 Screening compound: N-(3-chlorophenyl)-2-{2,4'-dioxo-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}acetamide
E897-0272 Screening compound: N-(3-chlorophenyl)-2-{2,4'-dioxo-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E897-0272
N-(3-chlorophenyl)-2-{2,4'-dioxo-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E897-0272

Molecular Formula

C24H18ClN3O3S (C24 H18 ClN3 O3 S)

Compound Name

N-(3-chlorophenyl)-2-{2,4'-dioxo-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}acetamide

IUPAC name

N-(3-chlorophenyl)-2-{24'-dioxo-3'-phenyl-12-dihydrospiro[indole-32'-[13]thiazolidin]-1-yl}acetamide

SMILES

O=C(CN(C(C1(N2c3ccccc3)SCC2=O)=O)c2c1cccc2)Nc1cccc(Cl)c1

InChI

InChI=1S/C24H18ClN3O3S/c25-16-7-6-8-17(13-16)26-21(29)14-27-20-12-5-4-11-19(20)24(23(27)31)28(22(30)15-32-24)18-9-2-1-3-10-18/h1-13H,14-15H2,(H,26,29)/t24-/m0/s1

InChI Key

MYVVXSIMBDUDBB-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD14926141

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.315

Distribution Coefficient, logD

4.314

Water Solubility, LogSw

-4.55

Polar Surface Area

54.185

Acid Dissociation Constant (pKa)

10.63

Base Dissociation Constant (pKb)

-0.43

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

E897-0272 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E897-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E897-0272?
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What is the minimum amount of E897-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E897-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E897-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E897-0272 available by request