E897-0532 Screening compound: 3'-(3,4-difluorophenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

E897-0532 Screening compound: 3'-(3,4-difluorophenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione
E897-0532 Screening compound: 3'-(3,4-difluorophenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound E897-0532
3'-(3,4-difluorophenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E897-0532

Molecular Formula

C24H15F5N2O2S (C24 H15 F5 N2 O2 S)

Compound Name

3'-(3,4-difluorophenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

IUPAC name

3'-(34-difluorophenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-12-dihydrospiro[indole-32'-[13]thiazolidine]-24'-dione

SMILES

O=C(CSC1(c(cccc2)c2N2Cc3cc(C(F)(F)F)ccc3)C2=O)N1c(cc1)cc(F)c1F

InChI

InChI=1S/C24H15F5N2O2S/c25-18-9-8-16(11-19(18)26)31-21(32)13-34-23(31)17-6-1-2-7-20(17)30(22(23)33)12-14-4-3-5-15(10-14)24(27,28)29/h1-11H,12-13H2/t23-/m0/s1

InChI Key

BHVNKQILBQMNOT-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD14926343

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.401

Distribution Coefficient, logD

5.401

Water Solubility, LogSw

-5.84

Polar Surface Area

31.036

Acid Dissociation Constant (pKa)

13.21

Base Dissociation Constant (pKb)

-6.25

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

E897-0532 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Human Proteases Annotated Library (2868 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with E897-0532 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E897-0532?
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What is the minimum amount of E897-0532 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E897-0532
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E897-0532
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E897-0532 available by request