E897-0555 Screening compound: N-(3,5-dimethylphenyl)-2-[3'-(3,5-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]acetamide

E897-0555 Screening compound: N-(3,5-dimethylphenyl)-2-[3'-(3,5-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]acetamide
E897-0555 Screening compound: N-(3,5-dimethylphenyl)-2-[3'-(3,5-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E897-0555
N-(3,5-dimethylphenyl)-2-[3'-(3,5-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E897-0555

Molecular Formula

C28H27N3O3S (C28 H27 N3 O3 S)

Compound Name

N-(3,5-dimethylphenyl)-2-[3'-(3,5-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]acetamide

IUPAC name

N-(35-dimethylphenyl)-2-[3'-(35-dimethylphenyl)-24'-dioxo-12-dihydrospiro[indole-32'-[13]thiazolidin]-1-yl]acetamide

SMILES

Cc1cc(NC(CN(C(C2(N3c4cc(C)cc(C)c4)SCC3=O)=O)c3c2cccc3)=O)cc(C)c1

InChI

InChI=1S/C28H27N3O3S/c1-17-9-18(2)12-21(11-17)29-25(32)15-30-24-8-6-5-7-23(24)28(27(30)34)31(26(33)16-35-28)22-13-19(3)10-20(4)14-22/h5-14H,15-16H2,1-4H3,(H,29,32)/t28-/m0/s1

InChI Key

WCKOREDAWXERDE-NDEPHWFRSA-N

MDL Number (MFCD)

MFCD14926357

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.411

Distribution Coefficient, logD

5.411

Water Solubility, LogSw

-5.34

Polar Surface Area

54.185

Acid Dissociation Constant (pKa)

12.87

Base Dissociation Constant (pKb)

2.83

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

E897-0555 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E897-0555 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E897-0555?
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What is the minimum amount of E897-0555 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E897-0555
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E897-0555
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E897-0555 available by request