E898-2430 Screening compound: 3-[3-(3,5-difluorophenyl)-4-oxo-4H,5H-[1,2]oxazolo[5,4-d]pyrimidin-5-yl]-N-[(2,5-dimethoxyphenyl)methyl]propanamide
Chemical Structure Depiction of ChemDiv screening compound E898-2430
3-[3-(3,5-difluorophenyl)-4-oxo-4H,5H-[1,2]oxazolo[5,4-d]pyrimidin-5-yl]-N-[(2,5-dimethoxyphenyl)methyl]propanamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
E898-2430
Molecular Formula
C23H20F2N4O5 (C23 H20 F2 N4 O5)
Compound Name
3-[3-(3,5-difluorophenyl)-4-oxo-4H,5H-[1,2]oxazolo[5,4-d]pyrimidin-5-yl]-N-[(2,5-dimethoxyphenyl)methyl]propanamide
IUPAC name
3-[3-(35-difluorophenyl)-4-oxo-4H5H-[12]oxazolo[54-d]pyrimidin-5-yl]-N-[(25-dimethoxyphenyl)methyl]propanamide
SMILES
COc(cc1)cc(CNC(CCN(C=Nc2c3c(-c4cc(F)cc(F)c4)no2)C3=O)=O)c1OC
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
470.43
Hydrogen Bond Acceptors Count
9.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
9.00
Number of Nitrogen and Oxygen Atoms
9
Partition Coefficient, logP
2.776
Distribution Coefficient, logD
2.776
Water Solubility, LogSw
-3.31
Polar Surface Area
87.326
Acid Dissociation Constant (pKa)
13.17
Base Dissociation Constant (pKb)
3.34
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
21.70
E898-2430 in Drug Discovery
Included in Screening Libraries
Protein Kinases Inhibitors Library (36801 compounds)
Targeted Diversity Library (40567 compounds)
Peptidomimetic Library (37031 compounds)
Included in 1.7M Stock Database
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Nervous system
- Hemic and lymphatic
- Cardiovascular
- Kinases
- PPI modulators
- Mimetics
References: we are preparing a list of scientific research reports with E898-2430 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of E898-2430, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)