E899-0186 Screening compound: 3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-amine

E899-0186 Screening compound: 3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-amine
E899-0186 Screening compound: 3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound E899-0186
3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E899-0186

Molecular Formula

C19H15FN4O (C19 H15 FN4 O)

Compound Name

3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-amine

IUPAC name

3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-[12]oxazolo[54-d]pyrimidin-4-amine

SMILES

Cc1ccc(CNc2c(c(-c(cc3)ccc3F)no3)c3ncn2)cc1

InChI

InChI=1S/C19H15FN4O/c1-12-2-4-13(5-3-12)10-21-18-16-17(14-6-8-15(20)9-7-14)24-25-19(16)23-11-22-18/h2-9,11H,10H2,1H3,(H,21,22,23)

InChI Key

VTQWKPXPONMPCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14926716

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.932

Distribution Coefficient, logD

3.932

Water Solubility, LogSw

-4.21

Polar Surface Area

53.023

Acid Dissociation Constant (pKa)

16.48

Base Dissociation Constant (pKb)

2.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

E899-0186 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

Antiviral Annotated Library (21441 compounds)

Human Receptors Annotated Library (5376 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with E899-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E899-0186?
Check Price and Availability of E899-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E899-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E899-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E899-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E899-0186 available by request