E907-0011 Screening compound: 1-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]-3-[(oxolan-2-yl)methyl]urea

E907-0011 Screening compound: 1-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]-3-[(oxolan-2-yl)methyl]urea
E907-0011 Screening compound: 1-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]-3-[(oxolan-2-yl)methyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E907-0011
1-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]-3-[(oxolan-2-yl)methyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E907-0011

Molecular Formula

C21H29N5O2 (C21 H29 N5 O2)

Compound Name

1-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]-3-[(oxolan-2-yl)methyl]urea

IUPAC name

1-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]-3-[(oxolan-2-yl)methyl]urea

SMILES

Cc1c(cc(cc2)NC(NCC3OCCC3)=O)c2nc(N2CCN(C)CC2)c1

InChI

InChI=1S/C21H29N5O2/c1-15-12-20(26-9-7-25(2)8-10-26)24-19-6-5-16(13-18(15)19)23-21(27)22-14-17-4-3-11-28-17/h5-6,12-13,17H,3-4,7-11,14H2,1-2H3,(H2,22,23,27)/t17-/m1/s1

InChI Key

RNZADMYWAWARDK-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD14927057

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.018

Distribution Coefficient, logD

2.448

Water Solubility, LogSw

-3.15

Polar Surface Area

57.241

Acid Dissociation Constant (pKa)

12.46

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.40

E907-0011 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Purinergic Library (3321 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E907-0011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E907-0011?
Check Price and Availability of E907-0011, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E907-0011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E907-0011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E907-0011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E907-0011 available by request