E907-0023 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

E907-0023 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea
E907-0023 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E907-0023
1-[(4-fluorophenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E907-0023

Molecular Formula

C23H26FN5O (C23 H26 FN5 O)

Compound Name

1-[(4-fluorophenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

IUPAC name

1-[(4-fluorophenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

SMILES

Cc1c(cc(cc2)NC(NCc(cc3)ccc3F)=O)c2nc(N2CCN(C)CC2)c1

InChI

InChI=1S/C23H26FN5O/c1-16-13-22(29-11-9-28(2)10-12-29)27-21-8-7-19(14-20(16)21)26-23(30)25-15-17-3-5-18(24)6-4-17/h3-8,13-14H,9-12,15H2,1-2H3,(H2,25,26,30)

InChI Key

SWLDHCAWYLDOQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14927067

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.203

Distribution Coefficient, logD

3.633

Water Solubility, LogSw

-4.20

Polar Surface Area

48.587

Acid Dissociation Constant (pKa)

12.70

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

E907-0023 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

CNS Targets (44014 compounds)

Immunological Library (6760 compounds)

Purinergic Library (3321 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Immune system
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E907-0023 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E907-0023?
Check Price and Availability of E907-0023, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E907-0023 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E907-0023
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E907-0023
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E907-0023 available by request