E922-0344 Screening compound: 1-(3,4-dimethylphenyl)-N-(2-fluoro-5-nitrophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

E922-0344 Screening compound: 1-(3,4-dimethylphenyl)-N-(2-fluoro-5-nitrophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide
E922-0344 Screening compound: 1-(3,4-dimethylphenyl)-N-(2-fluoro-5-nitrophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-0344
1-(3,4-dimethylphenyl)-N-(2-fluoro-5-nitrophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-0344

Molecular Formula

C23H24FN5O3 (C23 H24 FN5 O3)

Compound Name

1-(3,4-dimethylphenyl)-N-(2-fluoro-5-nitrophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

IUPAC name

1-(34-dimethylphenyl)-N-(2-fluoro-5-nitrophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

SMILES

Cc(cc1)c(C)cc1-n1ncc(C(Nc(cc(cc2)[N+]([O-])=O)c2F)=O)c1C1CCNCC1

InChI

InChI=1S/C23H24FN5O3/c1-14-3-4-17(11-15(14)2)28-22(16-7-9-25-10-8-16)19(13-26-28)23(30)27-21-12-18(29(31)32)5-6-20(21)24/h3-6,11-13,16,25H,7-10H2,1-2H3,(H,27,30)

InChI Key

SUINCCMPYMJJNT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928324

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

437.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.943

Distribution Coefficient, logD

3.943

Water Solubility, LogSw

-3.86

Polar Surface Area

80.989

Acid Dissociation Constant (pKa)

6.97

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

E922-0344 in Drug Discovery

Included in Screening Libraries

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E922-0344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-0344?
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What is the minimum amount of E922-0344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-0344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-0344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-0344 available by request