E922-0423 Screening compound: N-(2,4-dimethoxyphenethyl)-1-(3,4-dimethylphenyl)-5-(4-piperidyl)-1H-pyrazole-4-carboxamide

E922-0423 Screening compound: N-(2,4-dimethoxyphenethyl)-1-(3,4-dimethylphenyl)-5-(4-piperidyl)-1H-pyrazole-4-carboxamide
E922-0423 Screening compound: N-(2,4-dimethoxyphenethyl)-1-(3,4-dimethylphenyl)-5-(4-piperidyl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-0423
N-(2,4-dimethoxyphenethyl)-1-(3,4-dimethylphenyl)-5-(4-piperidyl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-0423

Molecular Formula

C27H34N4O3 (C27 H34 N4 O3)

Compound Name

N-(2,4-dimethoxyphenethyl)-1-(3,4-dimethylphenyl)-5-(4-piperidyl)-1H-pyrazole-4-carboxamide

IUPAC name

N-[2-(24-dimethoxyphenyl)ethyl]-1-(34-dimethylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

SMILES

Cc(cc1)c(C)cc1-n1ncc(C(NCCc(ccc(OC)c2)c2OC)=O)c1C1CCNCC1

InChI

InChI=1S/C27H34N4O3/c1-18-5-7-22(15-19(18)2)31-26(21-9-12-28-13-10-21)24(17-30-31)27(32)29-14-11-20-6-8-23(33-3)16-25(20)34-4/h5-8,15-17,21,28H,9-14H2,1-4H3,(H,29,32)

InChI Key

CELQRNNAJSGUNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928343

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

462.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.885

Distribution Coefficient, logD

0.404

Water Solubility, LogSw

-3.85

Polar Surface Area

64.643

Acid Dissociation Constant (pKa)

13.33

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.74

E922-0423 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E922-0423 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-0423?
Check Price and Availability of E922-0423, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E922-0423 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-0423
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-0423
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-0423 available by request