E922-0958 Screening compound: 1-(3-chloro-4-methylphenyl)-N-(4-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

E922-0958 Screening compound: 1-(3-chloro-4-methylphenyl)-N-(4-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide
E922-0958 Screening compound: 1-(3-chloro-4-methylphenyl)-N-(4-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-0958
1-(3-chloro-4-methylphenyl)-N-(4-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-0958

Molecular Formula

C24H27ClN4O2 (C24 H27 ClN4 O2)

Compound Name

1-(3-chloro-4-methylphenyl)-N-(4-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

IUPAC name

1-(3-chloro-4-methylphenyl)-N-(4-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

SMILES

CCOc(cc1)ccc1NC(c1c(C2CCNCC2)n(-c2cc(Cl)c(C)cc2)nc1)=O

InChI

InChI=1S/C24H27ClN4O2/c1-3-31-20-8-5-18(6-9-20)28-24(30)21-15-27-29(19-7-4-16(2)22(25)14-19)23(21)17-10-12-26-13-11-17/h4-9,14-15,17,26H,3,10-13H2,1-2H3,(H,28,30)

InChI Key

JLNYPGMIDQCBLL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928462

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

438.96

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.195

Distribution Coefficient, logD

0.714

Water Solubility, LogSw

-4.49

Polar Surface Area

55.429

Acid Dissociation Constant (pKa)

11.15

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E922-0958 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

CNS targets activity set (6557 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E922-0958 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-0958?
Check Price and Availability of E922-0958, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E922-0958 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-0958
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-0958
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-0958 available by request