E922-1571 Screening compound: 1-(3-fluorophenyl)-5-(piperidin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide

E922-1571 Screening compound: 1-(3-fluorophenyl)-5-(piperidin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide
E922-1571 Screening compound: 1-(3-fluorophenyl)-5-(piperidin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-1571
1-(3-fluorophenyl)-5-(piperidin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-1571

Molecular Formula

C22H20F4N4O (C22 H20 F4 N4 O)

Compound Name

1-(3-fluorophenyl)-5-(piperidin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide

IUPAC name

1-(3-fluorophenyl)-5-(piperidin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide

SMILES

O=C(c1c(C2CCNCC2)n(-c2cccc(F)c2)nc1)Nc1cc(C(F)(F)F)ccc1

InChI

InChI=1S/C22H20F4N4O/c23-16-4-2-6-18(12-16)30-20(14-7-9-27-10-8-14)19(13-28-30)21(31)29-17-5-1-3-15(11-17)22(24,25)26/h1-6,11-14,27H,7-10H2,(H,29,31)

InChI Key

XLNCUWZKDPEQNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928566

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

432.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.690

Distribution Coefficient, logD

0.209

Water Solubility, LogSw

-3.95

Polar Surface Area

48.305

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

E922-1571 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

CNS Targets (44014 compounds)

CNS targets activity set (6557 compounds)

GABA Library (7115 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Eye
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Proteases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E922-1571 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-1571?
Check Price and Availability of E922-1571, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E922-1571 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-1571
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-1571
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-1571 available by request