E922-1705 Screening compound: N-(4-bromo-2-fluorophenyl)-1-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

E922-1705 Screening compound: N-(4-bromo-2-fluorophenyl)-1-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide
E922-1705 Screening compound: N-(4-bromo-2-fluorophenyl)-1-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-1705
N-(4-bromo-2-fluorophenyl)-1-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-1705

Molecular Formula

C21H19BrF2N4O (C21 H19 BrF2 N4 O)

Compound Name

N-(4-bromo-2-fluorophenyl)-1-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

IUPAC name

N-(4-bromo-2-fluorophenyl)-1-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

SMILES

O=C(c1c(C2CCNCC2)n(-c(cc2)ccc2F)nc1)Nc(ccc(Br)c1)c1F

InChI

InChI=1S/C21H19BrF2N4O/c22-14-1-6-19(18(24)11-14)27-21(29)17-12-26-28(16-4-2-15(23)3-5-16)20(17)13-7-9-25-10-8-13/h1-6,11-13,25H,7-10H2,(H,27,29)

InChI Key

UGMVGSXSXFMXIZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928637

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

461.31

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.484

Distribution Coefficient, logD

0.003

Water Solubility, LogSw

-3.59

Polar Surface Area

47.607

Acid Dissociation Constant (pKa)

7.79

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

E922-1705 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E922-1705 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-1705?
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What is the minimum amount of E922-1705 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-1705
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-1705
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-1705 available by request