E922-2214 Screening compound: methyl 4-[1-(3-chloro-2-methylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-amido]benzoate

E922-2214 Screening compound: methyl 4-[1-(3-chloro-2-methylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-amido]benzoate
E922-2214 Screening compound: methyl 4-[1-(3-chloro-2-methylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-amido]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-2214
methyl 4-[1-(3-chloro-2-methylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-amido]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-2214

Molecular Formula

C24H25ClN4O3 (C24 H25 ClN4 O3)

Compound Name

methyl 4-[1-(3-chloro-2-methylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-amido]benzoate

IUPAC name

methyl 4-[1-(3-chloro-2-methylphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-amido]benzoate

SMILES

Cc(c(-n1ncc(C(Nc(cc2)ccc2C(OC)=O)=O)c1C1CCNCC1)ccc1)c1Cl

InChI

InChI=1S/C24H25ClN4O3/c1-15-20(25)4-3-5-21(15)29-22(16-10-12-26-13-11-16)19(14-27-29)23(30)28-18-8-6-17(7-9-18)24(31)32-2/h3-9,14,16,26H,10-13H2,1-2H3,(H,28,30)

InChI Key

SSQQNSIIUYDAAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928717

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

452.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.700

Distribution Coefficient, logD

0.219

Water Solubility, LogSw

-4.17

Polar Surface Area

69.178

Acid Dissociation Constant (pKa)

9.78

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

E922-2214 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E922-2214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-2214?
Check Price and Availability of E922-2214, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E922-2214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-2214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-2214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-2214 available by request