E941-0075 Screening compound: 1-(4-fluorophenyl)-4-{8-methyl-1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazine

E941-0075 Screening compound: 1-(4-fluorophenyl)-4-{8-methyl-1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazine
E941-0075 Screening compound: 1-(4-fluorophenyl)-4-{8-methyl-1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E941-0075
1-(4-fluorophenyl)-4-{8-methyl-1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E941-0075

Molecular Formula

C23H21FN4O (C23 H21 FN4 O)

Compound Name

1-(4-fluorophenyl)-4-{8-methyl-1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazine

IUPAC name

1-(4-fluorophenyl)-4-{8-methyl-1H-pyrrolo[32-h]quinoline-2-carbonyl}piperazine

SMILES

Cc1ccc(ccc2c3[nH]c(C(N(CC4)CCN4c(cc4)ccc4F)=O)c2)c3n1

InChI

InChI=1S/C23H21FN4O/c1-15-2-3-16-4-5-17-14-20(26-22(17)21(16)25-15)23(29)28-12-10-27(11-13-28)19-8-6-18(24)7-9-19/h2-9,14,26H,10-13H2,1H3

InChI Key

OPCIENWVNHUUBO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27093488

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.300

Distribution Coefficient, logD

4.290

Water Solubility, LogSw

-4.25

Polar Surface Area

39.174

Acid Dissociation Constant (pKa)

15.91

Base Dissociation Constant (pKb)

5.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

E941-0075 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E941-0075 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E941-0075?
Check Price and Availability of E941-0075, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E941-0075 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E941-0075
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E941-0075
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E941-0075 available by request