E944-0073 Screening compound: 8-{3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-yl}-1,4-dioxa-8-azaspiro[4.5]decane

E944-0073 Screening compound: 8-{3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-yl}-1,4-dioxa-8-azaspiro[4.5]decane
E944-0073 Screening compound: 8-{3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-yl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound E944-0073
8-{3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-yl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E944-0073

Molecular Formula

C13H16N4O3 (C13 H16 N4 O3)

Compound Name

8-{3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-yl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{3-methyl-[12]oxazolo[54-d]pyrimidin-4-yl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

Cc1noc2ncnc(N(CC3)CCC33OCCO3)c12

InChI

InChI=1S/C13H16N4O3/c1-9-10-11(14-8-15-12(10)20-16-9)17-4-2-13(3-5-17)18-6-7-19-13/h8H,2-7H2,1H3

InChI Key

PXSIXKOHAZVITJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14929160

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

276.3

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.289

Distribution Coefficient, logD

1.289

Water Solubility, LogSw

-1.32

Polar Surface Area

60.049

Acid Dissociation Constant (pKa)

21.61

Base Dissociation Constant (pKb)

3.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.50

E944-0073 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E944-0073 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E944-0073?
Check Price and Availability of E944-0073, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E944-0073 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E944-0073
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E944-0073
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E944-0073 available by request