E947-0483 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3-(2-methylpropyl)-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

E947-0483 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3-(2-methylpropyl)-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide
E947-0483 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3-(2-methylpropyl)-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E947-0483
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3-(2-methylpropyl)-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E947-0483

Molecular Formula

C22H27N3O5 (C22 H27 N3 O5)

Compound Name

N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3-(2-methylpropyl)-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-[2-(34-dimethoxyphenyl)ethyl]-6-methyl-3-(2-methylpropyl)-4-oxo-3H4H-furo[23-d]pyrimidine-5-carboxamide

SMILES

CC(C)CN(C=Nc1c2c(C(NCCc(cc3)cc(OC)c3OC)=O)c(C)o1)C2=O

InChI

InChI=1S/C22H27N3O5/c1-13(2)11-25-12-24-21-19(22(25)27)18(14(3)30-21)20(26)23-9-8-15-6-7-16(28-4)17(10-15)29-5/h6-7,10,12-13H,8-9,11H2,1-5H3,(H,23,26)

InChI Key

YUJZZTRYZKMFEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27093861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.725

Distribution Coefficient, logD

1.725

Water Solubility, LogSw

-2.21

Polar Surface Area

73.509

Acid Dissociation Constant (pKa)

12.86

Base Dissociation Constant (pKb)

-0.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

E947-0483 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E947-0483 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E947-0483?
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What is the minimum amount of E947-0483 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E947-0483
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E947-0483
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E947-0483 available by request