E947-3011 Screening compound: 6-methyl-4-oxo-3-(1-phenylethyl)-N-(6-sulfamoylpyridin-3-yl)-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

E947-3011 Screening compound: 6-methyl-4-oxo-3-(1-phenylethyl)-N-(6-sulfamoylpyridin-3-yl)-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide
E947-3011 Screening compound: 6-methyl-4-oxo-3-(1-phenylethyl)-N-(6-sulfamoylpyridin-3-yl)-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E947-3011
6-methyl-4-oxo-3-(1-phenylethyl)-N-(6-sulfamoylpyridin-3-yl)-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E947-3011

Molecular Formula

C21H19N5O5S (C21 H19 N5 O5 S)

Compound Name

6-methyl-4-oxo-3-(1-phenylethyl)-N-(6-sulfamoylpyridin-3-yl)-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

6-methyl-4-oxo-3-(1-phenylethyl)-N-(6-sulfamoylpyridin-3-yl)-3H4H-furo[23-d]pyrimidine-5-carboxamide

SMILES

CC(c1ccccc1)N(C=Nc1c2c(C(Nc(cc3)cnc3S(N)(=O)=O)=O)c(C)o1)C2=O

InChI

InChI=1S/C21H19N5O5S/c1-12(14-6-4-3-5-7-14)26-11-24-20-18(21(26)28)17(13(2)31-20)19(27)25-15-8-9-16(23-10-15)32(22,29)30/h3-12H,1-2H3,(H,25,27)(H2,22,29,30)/t12-/m0/s1

InChI Key

XSHNZTWKMLGMSB-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD27094050

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.48

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.604

Distribution Coefficient, logD

1.532

Water Solubility, LogSw

-2.33

Polar Surface Area

115.835

Acid Dissociation Constant (pKa)

8.14

Base Dissociation Constant (pKb)

-1.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

14.30

E947-3011 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E947-3011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E947-3011?
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What is the minimum amount of E947-3011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E947-3011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E947-3011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E947-3011 available by request