E948-0463 Screening compound: methyl 2-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-amido]benzoate

E948-0463 Screening compound: methyl 2-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-amido]benzoate
E948-0463 Screening compound: methyl 2-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-amido]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-0463
methyl 2-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-amido]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-0463

Molecular Formula

C20H20N4O5 (C20 H20 N4 O5)

Compound Name

methyl 2-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-amido]benzoate

IUPAC name

methyl 2-[6-methyl-4-(morpholin-4-yl)furo[23-d]pyrimidine-5-amido]benzoate

SMILES

Cc1c(C(Nc(cccc2)c2C(OC)=O)=O)c2c(N3CCOCC3)ncnc2o1

InChI

InChI=1S/C20H20N4O5/c1-12-15(18(25)23-14-6-4-3-5-13(14)20(26)27-2)16-17(21-11-22-19(16)29-12)24-7-9-28-10-8-24/h3-6,11H,7-10H2,1-2H3,(H,23,25)

InChI Key

BKMXCHGVTLVPRU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14929873

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.663

Distribution Coefficient, logD

2.653

Water Solubility, LogSw

-3.37

Polar Surface Area

83.030

Acid Dissociation Constant (pKa)

9.05

Base Dissociation Constant (pKb)

0.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

E948-0463 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E948-0463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-0463?
Check Price and Availability of E948-0463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E948-0463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-0463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-0463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-0463 available by request