E948-0605 Screening compound: N-{3-[butyl(ethyl)amino]propyl}-6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

E948-0605 Screening compound: N-{3-[butyl(ethyl)amino]propyl}-6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide
E948-0605 Screening compound: N-{3-[butyl(ethyl)amino]propyl}-6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-0605
N-{3-[butyl(ethyl)amino]propyl}-6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-0605

Molecular Formula

C21H33N5O3 (C21 H33 N5 O3)

Compound Name

N-{3-[butyl(ethyl)amino]propyl}-6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-{3-[butyl(ethyl)amino]propyl}-6-methyl-4-(morpholin-4-yl)furo[23-d]pyrimidine-5-carboxamide

SMILES

CCCCN(CC)CCCNC(c1c(C)oc2ncnc(N3CCOCC3)c12)=O

InChI

InChI=1S/C21H33N5O3/c1-4-6-9-25(5-2)10-7-8-22-20(27)17-16(3)29-21-18(17)19(23-15-24-21)26-11-13-28-14-12-26/h15H,4-14H2,1-3H3,(H,22,27)

InChI Key

VVIRFJXUIYPERR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14929952

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.438

Distribution Coefficient, logD

-0.254

Water Solubility, LogSw

-2.56

Polar Surface Area

67.654

Acid Dissociation Constant (pKa)

15.96

Base Dissociation Constant (pKb)

10.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.70

E948-0605 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E948-0605 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-0605?
Check Price and Availability of E948-0605, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E948-0605 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-0605
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-0605
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-0605 available by request