E948-1252 Screening compound: 2,6-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

E948-1252 Screening compound: 2,6-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide
E948-1252 Screening compound: 2,6-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-1252
2,6-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-1252

Molecular Formula

C17H19N5O4 (C17 H19 N5 O4)

Compound Name

2,6-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

26-dimethyl-N-(5-methyl-12-oxazol-3-yl)-4-(morpholin-4-yl)furo[23-d]pyrimidine-5-carboxamide

SMILES

Cc1cc(NC(c2c(C)oc3nc(C)nc(N4CCOCC4)c23)=O)no1

InChI

InChI=1S/C17H19N5O4/c1-9-8-12(21-26-9)20-16(23)13-10(2)25-17-14(13)15(18-11(3)19-17)22-4-6-24-7-5-22/h8H,4-7H2,1-3H3,(H,20,21,23)

InChI Key

KEVIZYHKPFFJKO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27094068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.37

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.504

Distribution Coefficient, logD

2.491

Water Solubility, LogSw

-2.87

Polar Surface Area

82.724

Acid Dissociation Constant (pKa)

8.92

Base Dissociation Constant (pKb)

2.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

E948-1252 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E948-1252 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-1252?
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What is the minimum amount of E948-1252 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-1252
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-1252
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-1252 available by request