E948-1254 Screening compound: N-(2-fluorophenyl)-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

E948-1254 Screening compound: N-(2-fluorophenyl)-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide
E948-1254 Screening compound: N-(2-fluorophenyl)-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-1254
N-(2-fluorophenyl)-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-1254

Molecular Formula

C19H19FN4O3 (C19 H19 FN4 O3)

Compound Name

N-(2-fluorophenyl)-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-(2-fluorophenyl)-26-dimethyl-4-(morpholin-4-yl)furo[23-d]pyrimidine-5-carboxamide

SMILES

Cc1c(C(Nc(cccc2)c2F)=O)c2c(N3CCOCC3)nc(C)nc2o1

InChI

InChI=1S/C19H19FN4O3/c1-11-15(18(25)23-14-6-4-3-5-13(14)20)16-17(24-7-9-26-10-8-24)21-12(2)22-19(16)27-11/h3-6H,7-10H2,1-2H3,(H,23,25)

InChI Key

UTTLGTKKOIWNSV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14930101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.940

Distribution Coefficient, logD

2.940

Water Solubility, LogSw

-3.48

Polar Surface Area

60.230

Acid Dissociation Constant (pKa)

11.07

Base Dissociation Constant (pKb)

2.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

E948-1254 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E948-1254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-1254?
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What is the minimum amount of E948-1254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-1254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-1254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-1254 available by request