E948-1610 Screening compound: N-{3-[butyl(phenyl)amino]propyl}-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

E948-1610 Screening compound: N-{3-[butyl(phenyl)amino]propyl}-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide
E948-1610 Screening compound: N-{3-[butyl(phenyl)amino]propyl}-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-1610
N-{3-[butyl(phenyl)amino]propyl}-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-1610

Molecular Formula

C26H35N5O3 (C26 H35 N5 O3)

Compound Name

N-{3-[butyl(phenyl)amino]propyl}-2,6-dimethyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-{3-[butyl(phenyl)amino]propyl}-26-dimethyl-4-(morpholin-4-yl)furo[23-d]pyrimidine-5-carboxamide

SMILES

CCCCN(CCCNC(c1c(C)oc2nc(C)nc(N3CCOCC3)c12)=O)c1ccccc1

InChI

InChI=1S/C26H35N5O3/c1-4-5-13-30(21-10-7-6-8-11-21)14-9-12-27-25(32)22-19(2)34-26-23(22)24(28-20(3)29-26)31-15-17-33-18-16-31/h6-8,10-11H,4-5,9,12-18H2,1-3H3,(H,27,32)

InChI Key

IJUFRTZJGZFJDL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14930163

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.121

Distribution Coefficient, logD

4.096

Water Solubility, LogSw

-4.26

Polar Surface Area

65.335

Acid Dissociation Constant (pKa)

15.39

Base Dissociation Constant (pKb)

6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

E948-1610 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E948-1610 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-1610?
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What is the minimum amount of E948-1610 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-1610
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-1610
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-1610 available by request