E950-0154 Screening compound: 1-[4-(4-{1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazin-1-yl)phenyl]ethan-1-one

E950-0154 Screening compound: 1-[4-(4-{1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazin-1-yl)phenyl]ethan-1-one
E950-0154 Screening compound: 1-[4-(4-{1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazin-1-yl)phenyl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E950-0154
1-[4-(4-{1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazin-1-yl)phenyl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E950-0154

Molecular Formula

C24H22N4O2 (C24 H22 N4 O2)

Compound Name

1-[4-(4-{1H-pyrrolo[3,2-h]quinoline-2-carbonyl}piperazin-1-yl)phenyl]ethan-1-one

IUPAC name

1-[4-(4-{1H-pyrrolo[32-h]quinoline-2-carbonyl}piperazin-1-yl)phenyl]ethan-1-one

SMILES

CC(c(cc1)ccc1N(CC1)CCN1C(c1cc(ccc2cccnc22)c2[nH]1)=O)=O

InChI

InChI=1S/C24H22N4O2/c1-16(29)17-6-8-20(9-7-17)27-11-13-28(14-12-27)24(30)21-15-19-5-4-18-3-2-10-25-22(18)23(19)26-21/h2-10,15,26H,11-14H2,1H3

InChI Key

MCTCTMTVDPGJCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27094085

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.243

Distribution Coefficient, logD

3.243

Water Solubility, LogSw

-3.23

Polar Surface Area

53.627

Acid Dissociation Constant (pKa)

15.76

Base Dissociation Constant (pKb)

4.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

E950-0154 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-HIV1 Library (19540 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E950-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E950-0154?
Check Price and Availability of E950-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E950-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E950-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E950-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E950-0154 available by request