E966-1485 Screening compound: N-(4-chlorophenyl)-1-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)sulfonyl]piperidine-4-carboxamide

E966-1485 Screening compound: N-(4-chlorophenyl)-1-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)sulfonyl]piperidine-4-carboxamide
E966-1485 Screening compound: N-(4-chlorophenyl)-1-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)sulfonyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E966-1485
N-(4-chlorophenyl)-1-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)sulfonyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E966-1485

Molecular Formula

C21H22ClN3O4S2 (C21 H22 ClN3 O4 S2)

Compound Name

N-(4-chlorophenyl)-1-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)sulfonyl]piperidine-4-carboxamide

IUPAC name

N-(4-chlorophenyl)-1-[(2-methyl-3-oxo-34-dihydro-2H-14-benzothiazin-6-yl)sulfonyl]piperidine-4-carboxamide

SMILES

CC1Sc(ccc(S(N(CC2)CCC2C(Nc(cc2)ccc2Cl)=O)(=O)=O)c2)c2NC1=O

InChI

InChI=1S/C21H22ClN3O4S2/c1-13-20(26)24-18-12-17(6-7-19(18)30-13)31(28,29)25-10-8-14(9-11-25)21(27)23-16-4-2-15(22)3-5-16/h2-7,12-14H,8-11H2,1H3,(H,23,27)(H,24,26)/t13-/m1/s1

InChI Key

LHWHQLKTFGYSDZ-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD14933866

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.01

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.475

Distribution Coefficient, logD

3.474

Water Solubility, LogSw

-3.95

Polar Surface Area

79.918

Acid Dissociation Constant (pKa)

10.28

Base Dissociation Constant (pKb)

-0.01

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

E966-1485 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

CNS targets activity set (6557 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Anti-HIV1 Library (19540 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with E966-1485 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E966-1485?
Check Price and Availability of E966-1485, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E966-1485 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E966-1485
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E966-1485
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E966-1485 available by request