E973-0289 Screening compound: 1-(2,5-dimethylphenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-c]quinazolin-5-yl}piperazine

E973-0289 Screening compound: 1-(2,5-dimethylphenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-c]quinazolin-5-yl}piperazine
E973-0289 Screening compound: 1-(2,5-dimethylphenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-c]quinazolin-5-yl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E973-0289
1-(2,5-dimethylphenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-c]quinazolin-5-yl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E973-0289

Molecular Formula

C23H26N6 (C23 H26 N6)

Compound Name

1-(2,5-dimethylphenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-c]quinazolin-5-yl}piperazine

IUPAC name

1-(25-dimethylphenyl)-4-{3-ethyl-[124]triazolo[43-c]quinazolin-5-yl}piperazine

SMILES

CCc1nnc2n1c(N(CC1)CCN1c1c(C)ccc(C)c1)nc1c2cccc1

InChI

InChI=1S/C23H26N6/c1-4-21-25-26-22-18-7-5-6-8-19(18)24-23(29(21)22)28-13-11-27(12-14-28)20-15-16(2)9-10-17(20)3/h5-10,15H,4,11-14H2,1-3H3

InChI Key

FHKIPSMJWICSFT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14933989

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.903

Distribution Coefficient, logD

4.884

Water Solubility, LogSw

-4.85

Polar Surface Area

37.200

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

6.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

E973-0289 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with E973-0289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E973-0289?
Check Price and Availability of E973-0289, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E973-0289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E973-0289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E973-0289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E973-0289 available by request