E973-0495 Screening compound: N-(2,5-diethoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

E973-0495 Screening compound: N-(2,5-diethoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine
E973-0495 Screening compound: N-(2,5-diethoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound E973-0495
N-(2,5-diethoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E973-0495

Molecular Formula

C19H19N5O2 (C19 H19 N5 O2)

Compound Name

N-(2,5-diethoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

IUPAC name

N-(25-diethoxyphenyl)-[124]triazolo[43-c]quinazolin-5-amine

SMILES

CCOc(cc1)cc(Nc2nc(cccc3)c3c3nncn23)c1OCC

InChI

InChI=1S/C19H19N5O2/c1-3-25-13-9-10-17(26-4-2)16(11-13)22-19-21-15-8-6-5-7-14(15)18-23-20-12-24(18)19/h5-12H,3-4H2,1-2H3,(H,21,22)

InChI Key

MVLPFAKJLQAYIE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14934034

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.634

Distribution Coefficient, logD

3.376

Water Solubility, LogSw

-3.95

Polar Surface Area

55.333

Acid Dissociation Constant (pKa)

16.21

Base Dissociation Constant (pKb)

7.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

E973-0495 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E973-0495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E973-0495?
Check Price and Availability of E973-0495, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E973-0495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E973-0495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E973-0495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E973-0495 available by request