E975-1327 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-4-(2,3-dimethylphenyl)piperazine

E975-1327 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-4-(2,3-dimethylphenyl)piperazine
E975-1327 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-4-(2,3-dimethylphenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E975-1327
1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-4-(2,3-dimethylphenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E975-1327

Molecular Formula

C25H31N3O2S (C25 H31 N3 O2 S)

Compound Name

1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}-4-(2,3-dimethylphenyl)piperazine

IUPAC name

1-{5H6H7H8H9H10H-cyclohepta[b]indole-2-sulfonyl}-4-(23-dimethylphenyl)piperazine

SMILES

Cc1cccc(N(CC2)CCN2S(c(cc2)cc3c2[nH]c2c3CCCCC2)(=O)=O)c1C

InChI

InChI=1S/C25H31N3O2S/c1-18-7-6-10-25(19(18)2)27-13-15-28(16-14-27)31(29,30)20-11-12-24-22(17-20)21-8-4-3-5-9-23(21)26-24/h6-7,10-12,17,26H,3-5,8-9,13-16H2,1-2H3

InChI Key

RRCZQFFUBCXLRF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14934230

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.437

Distribution Coefficient, logD

5.437

Water Solubility, LogSw

-5.49

Polar Surface Area

46.010

Acid Dissociation Constant (pKa)

18.51

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

E975-1327 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Annotated Library (21441 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E975-1327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E975-1327?
Check Price and Availability of E975-1327, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E975-1327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E975-1327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E975-1327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E975-1327 available by request