E977-0423 Screening compound: N-(2,4-dimethoxyphenyl)-1-[(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide

E977-0423 Screening compound: N-(2,4-dimethoxyphenyl)-1-[(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide
E977-0423 Screening compound: N-(2,4-dimethoxyphenyl)-1-[(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E977-0423
N-(2,4-dimethoxyphenyl)-1-[(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E977-0423

Molecular Formula

C24H29N3O6S (C24 H29 N3 O6 S)

Compound Name

N-(2,4-dimethoxyphenyl)-1-[(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide

IUPAC name

N-(24-dimethoxyphenyl)-1-[(2-oxo-2345-tetrahydro-1H-1-benzazepin-7-yl)sulfonyl]piperidine-4-carboxamide

SMILES

COc(cc1)cc(OC)c1NC(C(CC1)CCN1S(c(cc1)cc(CCC2)c1NC2=O)(=O)=O)=O

InChI

InChI=1S/C24H29N3O6S/c1-32-18-6-8-21(22(15-18)33-2)26-24(29)16-10-12-27(13-11-16)34(30,31)19-7-9-20-17(14-19)4-3-5-23(28)25-20/h6-9,14-16H,3-5,10-13H2,1-2H3,(H,25,28)(H,26,29)

InChI Key

JRNWTOJYRAPKCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14934674

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.178

Distribution Coefficient, logD

2.177

Water Solubility, LogSw

-2.96

Polar Surface Area

94.669

Acid Dissociation Constant (pKa)

10.31

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

E977-0423 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with E977-0423 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E977-0423?
Check Price and Availability of E977-0423, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E977-0423 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E977-0423
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E977-0423
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E977-0423 available by request