E984-1371 Screening compound: 4-[4-(2,3-dihydro-1H-indol-1-yl)-4-oxobutyl]-2-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

E984-1371 Screening compound: 4-[4-(2,3-dihydro-1H-indol-1-yl)-4-oxobutyl]-2-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one
E984-1371 Screening compound: 4-[4-(2,3-dihydro-1H-indol-1-yl)-4-oxobutyl]-2-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E984-1371
4-[4-(2,3-dihydro-1H-indol-1-yl)-4-oxobutyl]-2-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E984-1371

Molecular Formula

C19H22N4O2 (C19 H22 N4 O2)

Compound Name

4-[4-(2,3-dihydro-1H-indol-1-yl)-4-oxobutyl]-2-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

IUPAC name

4-[4-(23-dihydro-1H-indol-1-yl)-4-oxobutyl]-2-methyl-4H5H6H7H-pyrazolo[15-a]pyrimidin-5-one

SMILES

Cc1nn(CCC(N2CCCC(N(CC3)c4c3cccc4)=O)=O)c2c1

InChI

InChI=1S/C19H22N4O2/c1-14-13-17-22(19(25)9-12-23(17)20-14)10-4-7-18(24)21-11-8-15-5-2-3-6-16(15)21/h2-3,5-6,13H,4,7-12H2,1H3

InChI Key

KLWCVLINVLJGLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14936032

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.598

Distribution Coefficient, logD

1.598

Water Solubility, LogSw

-1.82

Polar Surface Area

43.500

Acid Dissociation Constant (pKa)

22.22

Base Dissociation Constant (pKb)

1.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

E984-1371 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E984-1371 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E984-1371?
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What is the minimum amount of E984-1371 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E984-1371
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E984-1371
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E984-1371 available by request