E984-2543 Screening compound: 2-(3-chlorophenyl)-4-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

E984-2543 Screening compound: 2-(3-chlorophenyl)-4-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one
E984-2543 Screening compound: 2-(3-chlorophenyl)-4-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E984-2543
2-(3-chlorophenyl)-4-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E984-2543

Molecular Formula

C23H23ClN6O2 (C23 H23 ClN6 O2)

Compound Name

2-(3-chlorophenyl)-4-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

IUPAC name

2-(3-chlorophenyl)-4-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H5H6H7H-pyrazolo[15-a]pyrimidin-5-one

SMILES

O=C(CN(c1cc(-c2cccc(Cl)c2)nn1CC1)C1=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C23H23ClN6O2/c24-18-5-3-4-17(14-18)19-15-21-29(22(31)7-9-30(21)26-19)16-23(32)28-12-10-27(11-13-28)20-6-1-2-8-25-20/h1-6,8,14-15H,7,9-13,16H2

InChI Key

MLMACIFTBKBGGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27095385

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.099

Distribution Coefficient, logD

3.090

Water Solubility, LogSw

-3.34

Polar Surface Area

56.185

Acid Dissociation Constant (pKa)

22.08

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

E984-2543 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E984-2543 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E984-2543?
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What is the minimum amount of E984-2543 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E984-2543
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E984-2543
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E984-2543 available by request