E999-1486 Screening compound: N-(5-chloro-2-methylphenyl)-2-[3-(2-methoxybenzoyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl]acetamide

E999-1486 Screening compound: N-(5-chloro-2-methylphenyl)-2-[3-(2-methoxybenzoyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl]acetamide
E999-1486 Screening compound: N-(5-chloro-2-methylphenyl)-2-[3-(2-methoxybenzoyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E999-1486
N-(5-chloro-2-methylphenyl)-2-[3-(2-methoxybenzoyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E999-1486

Molecular Formula

C26H22ClN3O4 (C26 H22 ClN3 O4)

Compound Name

N-(5-chloro-2-methylphenyl)-2-[3-(2-methoxybenzoyl)-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl]acetamide

IUPAC name

N-(5-chloro-2-methylphenyl)-2-[3-(2-methoxybenzoyl)-7-methyl-4-oxo-14-dihydro-18-naphthyridin-1-yl]acetamide

SMILES

Cc(ccc(Cl)c1)c1NC(CN(C=C1C(c(cccc2)c2OC)=O)c2nc(C)ccc2C1=O)=O

InChI

InChI=1S/C26H22ClN3O4/c1-15-8-10-17(27)12-21(15)29-23(31)14-30-13-20(24(32)18-6-4-5-7-22(18)34-3)25(33)19-11-9-16(2)28-26(19)30/h4-13H,14H2,1-3H3,(H,29,31)

InChI Key

ARUJMIGPIRJTPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14937334

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.93

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.668

Distribution Coefficient, logD

4.668

Water Solubility, LogSw

-4.78

Polar Surface Area

68.817

Acid Dissociation Constant (pKa)

10.68

Base Dissociation Constant (pKb)

-0.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

E999-1486 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E999-1486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E999-1486?
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What is the minimum amount of E999-1486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E999-1486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E999-1486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E999-1486 available by request