E999-1603 Screening compound: 3-(2,5-dimethylbenzoyl)-7-methyl-1-[(4-methylphenyl)methyl]-1,4-dihydro-1,8-naphthyridin-4-one

E999-1603 Screening compound: 3-(2,5-dimethylbenzoyl)-7-methyl-1-[(4-methylphenyl)methyl]-1,4-dihydro-1,8-naphthyridin-4-one
E999-1603 Screening compound: 3-(2,5-dimethylbenzoyl)-7-methyl-1-[(4-methylphenyl)methyl]-1,4-dihydro-1,8-naphthyridin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E999-1603
3-(2,5-dimethylbenzoyl)-7-methyl-1-[(4-methylphenyl)methyl]-1,4-dihydro-1,8-naphthyridin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E999-1603

Molecular Formula

C26H24N2O2 (C26 H24 N2 O2)

Compound Name

3-(2,5-dimethylbenzoyl)-7-methyl-1-[(4-methylphenyl)methyl]-1,4-dihydro-1,8-naphthyridin-4-one

IUPAC name

3-(25-dimethylbenzoyl)-7-methyl-1-[(4-methylphenyl)methyl]-14-dihydro-18-naphthyridin-4-one

SMILES

Cc1ccc(CN(C=C2C(c3c(C)ccc(C)c3)=O)c(nc(C)cc3)c3C2=O)cc1

InChI

InChI=1S/C26H24N2O2/c1-16-6-10-20(11-7-16)14-28-15-23(24(29)21-12-9-19(4)27-26(21)28)25(30)22-13-17(2)5-8-18(22)3/h5-13,15H,14H2,1-4H3

InChI Key

BJIIDFLHGVGWIZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27095575

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.881

Distribution Coefficient, logD

5.881

Water Solubility, LogSw

-5.39

Polar Surface Area

38.735

Acid Dissociation Constant (pKa)

26.18

Base Dissociation Constant (pKb)

-4.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

E999-1603 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E999-1603 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E999-1603?
Check Price and Availability of E999-1603, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E999-1603 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E999-1603
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E999-1603
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E999-1603 available by request