F038-0182 Screening compound: N-[(2,4-dimethoxyphenyl)methyl]-4-({2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}methyl)benzamide

F038-0182 Screening compound: N-[(2,4-dimethoxyphenyl)methyl]-4-({2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}methyl)benzamide
F038-0182 Screening compound: N-[(2,4-dimethoxyphenyl)methyl]-4-({2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}methyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F038-0182
N-[(2,4-dimethoxyphenyl)methyl]-4-({2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}methyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F038-0182

Molecular Formula

C24H22N4O5 (C24 H22 N4 O5)

Compound Name

N-[(2,4-dimethoxyphenyl)methyl]-4-({2,3-dioxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}methyl)benzamide

IUPAC name

N-[(24-dimethoxyphenyl)methyl]-4-({23-dioxo-1H2H3H4H-pyrido[23-b]pyrazin-4-yl}methyl)benzamide

SMILES

COc1cc(OC)c(CNC(c2ccc(CN(c3ncccc3NC3=O)C3=O)cc2)=O)cc1

InChI

InChI=1S/C24H22N4O5/c1-32-18-10-9-17(20(12-18)33-2)13-26-22(29)16-7-5-15(6-8-16)14-28-21-19(4-3-11-25-21)27-23(30)24(28)31/h3-12H,13-14H2,1-2H3,(H,26,29)(H,27,30)

InChI Key

QJOJGZPXVWAXAN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14937985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.458

Distribution Coefficient, logD

2.433

Water Solubility, LogSw

-2.86

Polar Surface Area

90.217

Acid Dissociation Constant (pKa)

8.61

Base Dissociation Constant (pKb)

0.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

F038-0182 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Immune system
Targets:
  • Proteases
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F038-0182 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F038-0182?
Check Price and Availability of F038-0182, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F038-0182 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F038-0182
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F038-0182
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F038-0182 available by request