F041-0482 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-{5-methoxy-1-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide

F041-0482 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-{5-methoxy-1-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide
F041-0482 Screening compound: N-(5-chloro-2-methoxyphenyl)-2-{5-methoxy-1-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F041-0482
N-(5-chloro-2-methoxyphenyl)-2-{5-methoxy-1-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F041-0482

Molecular Formula

C18H17ClN4O5 (C18 H17 ClN4 O5)

Compound Name

N-(5-chloro-2-methoxyphenyl)-2-{5-methoxy-1-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide

IUPAC name

N-(5-chloro-2-methoxyphenyl)-2-{5-methoxy-1-methyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl}acetamide

SMILES

CN(c(nccc1OC)c1C(N1CC(Nc(cc(cc2)Cl)c2OC)=O)=O)C1=O

InChI

InChI=1S/C18H17ClN4O5/c1-22-16-15(13(28-3)6-7-20-16)17(25)23(18(22)26)9-14(24)21-11-8-10(19)4-5-12(11)27-2/h4-8H,9H2,1-3H3,(H,21,24)

InChI Key

RBHQHWFWKNXVNO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09240042

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.81

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.566

Distribution Coefficient, logD

1.565

Water Solubility, LogSw

-3.01

Polar Surface Area

79.347

Acid Dissociation Constant (pKa)

9.83

Base Dissociation Constant (pKb)

2.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

F041-0482 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F041-0482 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F041-0482?
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What is the minimum amount of F041-0482 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F041-0482
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F041-0482
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F041-0482 available by request