F042-0871 Screening compound: 1-(2-{2-[(phenylcarbamoyl)amino]-1,3-thiazol-4-yl}acetyl)piperidine-4-carboxamide

F042-0871 Screening compound: 1-(2-{2-[(phenylcarbamoyl)amino]-1,3-thiazol-4-yl}acetyl)piperidine-4-carboxamide
F042-0871 Screening compound: 1-(2-{2-[(phenylcarbamoyl)amino]-1,3-thiazol-4-yl}acetyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F042-0871
1-(2-{2-[(phenylcarbamoyl)amino]-1,3-thiazol-4-yl}acetyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F042-0871

Molecular Formula

C18H21N5O3S (C18 H21 N5 O3 S)

Compound Name

1-(2-{2-[(phenylcarbamoyl)amino]-1,3-thiazol-4-yl}acetyl)piperidine-4-carboxamide

IUPAC name

1-(2-{2-[(phenylcarbamoyl)amino]-13-thiazol-4-yl}acetyl)piperidine-4-carboxamide

SMILES

NC(C(CC1)CCN1C(Cc1csc(NC(Nc2ccccc2)=O)n1)=O)=O

InChI

InChI=1S/C18H21N5O3S/c19-16(25)12-6-8-23(9-7-12)15(24)10-14-11-27-18(21-14)22-17(26)20-13-4-2-1-3-5-13/h1-5,11-12H,6-10H2,(H2,19,25)(H2,20,21,22,26)

InChI Key

CHIFGDBNYMBXDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08916833

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.724

Distribution Coefficient, logD

1.723

Water Solubility, LogSw

-2.27

Polar Surface Area

93.263

Acid Dissociation Constant (pKa)

10.59

Base Dissociation Constant (pKb)

0.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F042-0871 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F042-0871 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F042-0871?
Check Price and Availability of F042-0871, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F042-0871 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F042-0871
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F042-0871
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F042-0871 available by request