F042-1338 Screening compound: 1-cyclopentyl-3-{4-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}urea

F042-1338 Screening compound: 1-cyclopentyl-3-{4-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}urea
F042-1338 Screening compound: 1-cyclopentyl-3-{4-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F042-1338
1-cyclopentyl-3-{4-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F042-1338

Molecular Formula

C19H22N4O2S (C19 H22 N4 O2 S)

Compound Name

1-cyclopentyl-3-{4-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}urea

IUPAC name

1-cyclopentyl-3-{4-[2-(23-dihydro-1H-indol-1-yl)-2-oxoethyl]-13-thiazol-2-yl}urea

SMILES

O=C(Cc1csc(NC(NC2CCCC2)=O)n1)N(CC1)c2c1cccc2

InChI

InChI=1S/C19H22N4O2S/c24-17(23-10-9-13-5-1-4-8-16(13)23)11-15-12-26-19(21-15)22-18(25)20-14-6-2-3-7-14/h1,4-5,8,12,14H,2-3,6-7,9-11H2,(H2,20,21,22,25)

InChI Key

PTBZSFFYHZFEGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08917223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.734

Distribution Coefficient, logD

3.734

Water Solubility, LogSw

-4.00

Polar Surface Area

59.648

Acid Dissociation Constant (pKa)

11.23

Base Dissociation Constant (pKb)

1.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

F042-1338 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F042-1338 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F042-1338?
Check Price and Availability of F042-1338, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F042-1338 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F042-1338
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F042-1338
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F042-1338 available by request