F047-0494 Screening compound: 2-[(3-chloro-4-fluorophenyl)amino]-N-(4-methoxyphenyl)pyridine-4-carboxamide

F047-0494 Screening compound: 2-[(3-chloro-4-fluorophenyl)amino]-N-(4-methoxyphenyl)pyridine-4-carboxamide
F047-0494 Screening compound: 2-[(3-chloro-4-fluorophenyl)amino]-N-(4-methoxyphenyl)pyridine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F047-0494
2-[(3-chloro-4-fluorophenyl)amino]-N-(4-methoxyphenyl)pyridine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F047-0494

Molecular Formula

C19H15ClFN3O2 (C19 H15 ClFN3 O2)

Compound Name

2-[(3-chloro-4-fluorophenyl)amino]-N-(4-methoxyphenyl)pyridine-4-carboxamide

IUPAC name

2-[(3-chloro-4-fluorophenyl)amino]-N-(4-methoxyphenyl)pyridine-4-carboxamide

SMILES

COc(cc1)ccc1NC(c1cc(Nc(cc2)cc(Cl)c2F)ncc1)=O

InChI

InChI=1S/C19H15ClFN3O2/c1-26-15-5-2-13(3-6-15)24-19(25)12-8-9-22-18(10-12)23-14-4-7-17(21)16(20)11-14/h2-11H,1H3,(H,22,23)(H,24,25)

InChI Key

MTMZKRJHBFXESD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14938196

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

371.8

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.784

Distribution Coefficient, logD

4.784

Water Solubility, LogSw

-5.02

Polar Surface Area

49.401

Acid Dissociation Constant (pKa)

10.33

Base Dissociation Constant (pKb)

3.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

F047-0494 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F047-0494 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F047-0494?
Check Price and Availability of F047-0494, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F047-0494 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F047-0494
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F047-0494
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F047-0494 available by request