F048-0055 Screening compound: N-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzamide

F048-0055 Screening compound: N-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzamide
F048-0055 Screening compound: N-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F048-0055
N-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F048-0055

Molecular Formula

C23H24N4O3S2 (C23 H24 N4 O3 S2)

Compound Name

N-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzamide

IUPAC name

N-{5-methyl-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl}-4-(1234-tetrahydroisoquinoline-2-sulfonyl)benzamide

SMILES

CN(CC1)Cc2c1nc(NC(c(cc1)ccc1S(N(CC1)Cc3c1cccc3)(=O)=O)=O)s2

InChI

InChI=1S/C23H24N4O3S2/c1-26-12-11-20-21(15-26)31-23(24-20)25-22(28)17-6-8-19(9-7-17)32(29,30)27-13-10-16-4-2-3-5-18(16)14-27/h2-9H,10-15H2,1H3,(H,24,25,28)

InChI Key

OHUJAFHFGBDDRA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06682147

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.450

Distribution Coefficient, logD

3.450

Water Solubility, LogSw

-3.81

Polar Surface Area

69.580

Acid Dissociation Constant (pKa)

6.10

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

F048-0055 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with F048-0055 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F048-0055?
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What is the minimum amount of F048-0055 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F048-0055
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F048-0055
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F048-0055 available by request