F048-0247 Screening compound: N-{5-ethyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(propan-2-yloxy)benzamide

F048-0247 Screening compound: N-{5-ethyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(propan-2-yloxy)benzamide
F048-0247 Screening compound: N-{5-ethyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(propan-2-yloxy)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F048-0247
N-{5-ethyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(propan-2-yloxy)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F048-0247

Molecular Formula

C18H23N3O2S (C18 H23 N3 O2 S)

Compound Name

N-{5-ethyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-4-(propan-2-yloxy)benzamide

IUPAC name

N-{5-ethyl-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl}-4-(propan-2-yloxy)benzamide

SMILES

CCN(CC1)Cc2c1nc(NC(c(cc1)ccc1OC(C)C)=O)s2

InChI

InChI=1S/C18H23N3O2S/c1-4-21-10-9-15-16(11-21)24-18(19-15)20-17(22)13-5-7-14(8-6-13)23-12(2)3/h5-8,12H,4,9-11H2,1-3H3,(H,19,20,22)

InChI Key

DKHGARJLOSLTFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11731609

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

345.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.563

Distribution Coefficient, logD

3.563

Water Solubility, LogSw

-3.68

Polar Surface Area

45.070

Acid Dissociation Constant (pKa)

6.91

Base Dissociation Constant (pKb)

8.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

F048-0247 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F048-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F048-0247?
Check Price and Availability of F048-0247, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F048-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F048-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F048-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F048-0247 available by request