F048-0370 Screening compound: methyl 4-{[5-(propan-2-yl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}benzoate

F048-0370 Screening compound: methyl 4-{[5-(propan-2-yl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}benzoate
F048-0370 Screening compound: methyl 4-{[5-(propan-2-yl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound F048-0370
methyl 4-{[5-(propan-2-yl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F048-0370

Molecular Formula

C18H21N3O3S (C18 H21 N3 O3 S)

Compound Name

methyl 4-{[5-(propan-2-yl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}benzoate

IUPAC name

methyl 4-{[5-(propan-2-yl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]carbamoyl}benzoate

SMILES

CC(C)N(CC1)Cc2c1nc(NC(c(cc1)ccc1C(OC)=O)=O)s2

InChI

InChI=1S/C18H21N3O3S/c1-11(2)21-9-8-14-15(10-21)25-18(19-14)20-16(22)12-4-6-13(7-5-12)17(23)24-3/h4-7,11H,8-10H2,1-3H3,(H,19,20,22)

InChI Key

LHMLOZKNKWFKBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11986300

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

359.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.435

Distribution Coefficient, logD

3.435

Water Solubility, LogSw

-3.72

Polar Surface Area

59.769

Acid Dissociation Constant (pKa)

6.47

Base Dissociation Constant (pKb)

8.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

F048-0370 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F048-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F048-0370?
Check Price and Availability of F048-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F048-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F048-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F048-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F048-0370 available by request