F048-0651 Screening compound: N-{5-benzyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-3,5-dimethoxybenzamide

F048-0651 Screening compound: N-{5-benzyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-3,5-dimethoxybenzamide
F048-0651 Screening compound: N-{5-benzyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-3,5-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F048-0651
N-{5-benzyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-3,5-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F048-0651

Molecular Formula

C22H23N3O3S (C22 H23 N3 O3 S)

Compound Name

N-{5-benzyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-3,5-dimethoxybenzamide

IUPAC name

N-{5-benzyl-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl}-35-dimethoxybenzamide

SMILES

COc1cc(C(Nc2nc(CCN(Cc3ccccc3)C3)c3s2)=O)cc(OC)c1

InChI

InChI=1S/C22H23N3O3S/c1-27-17-10-16(11-18(12-17)28-2)21(26)24-22-23-19-8-9-25(14-20(19)29-22)13-15-6-4-3-5-7-15/h3-7,10-12H,8-9,13-14H2,1-2H3,(H,23,24,26)

InChI Key

MKTYGZFIGCQMQY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06585548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.319

Distribution Coefficient, logD

4.319

Water Solubility, LogSw

-4.21

Polar Surface Area

53.359

Acid Dissociation Constant (pKa)

7.82

Base Dissociation Constant (pKb)

7.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

F048-0651 in Drug Discovery

Included in Screening Libraries

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F048-0651 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F048-0651?
Check Price and Availability of F048-0651, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F048-0651 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F048-0651
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F048-0651
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F048-0651 available by request