F053-1151 Screening compound: 6-chloro-4-(3,4-dihydro-2H-1,4-benzothiazine-6-sulfonyl)-2-ethyl-3,4-dihydro-2H-1,4-benzoxazine

F053-1151 Screening compound: 6-chloro-4-(3,4-dihydro-2H-1,4-benzothiazine-6-sulfonyl)-2-ethyl-3,4-dihydro-2H-1,4-benzoxazine
F053-1151 Screening compound: 6-chloro-4-(3,4-dihydro-2H-1,4-benzothiazine-6-sulfonyl)-2-ethyl-3,4-dihydro-2H-1,4-benzoxazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F053-1151
6-chloro-4-(3,4-dihydro-2H-1,4-benzothiazine-6-sulfonyl)-2-ethyl-3,4-dihydro-2H-1,4-benzoxazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F053-1151

Molecular Formula

C18H19ClN2O3S2 (C18 H19 ClN2 O3 S2)

Compound Name

6-chloro-4-(3,4-dihydro-2H-1,4-benzothiazine-6-sulfonyl)-2-ethyl-3,4-dihydro-2H-1,4-benzoxazine

IUPAC name

6-chloro-4-(34-dihydro-2H-14-benzothiazine-6-sulfonyl)-2-ethyl-34-dihydro-2H-14-benzoxazine

SMILES

CCC(C1)Oc(ccc(Cl)c2)c2N1S(c(cc1)cc2c1SCCN2)(=O)=O

InChI

InChI=1S/C18H19ClN2O3S2/c1-2-13-11-21(16-9-12(19)3-5-17(16)24-13)26(22,23)14-4-6-18-15(10-14)20-7-8-25-18/h3-6,9-10,13,20H,2,7-8,11H2,1H3/t13-/m1/s1

InChI Key

JLXAXFXWOMCMTF-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD14938536

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.95

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.050

Distribution Coefficient, logD

4.050

Water Solubility, LogSw

-4.33

Polar Surface Area

50.113

Acid Dissociation Constant (pKa)

20.34

Base Dissociation Constant (pKb)

6.69

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

F053-1151 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F053-1151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F053-1151?
Check Price and Availability of F053-1151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F053-1151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F053-1151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F053-1151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F053-1151 available by request