F053-2916 Screening compound: cyclopropyl[6-(2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-1-ylsulfonyl)-2-methyl-2,3-dihydro-4H-1,4-benzothiazin-4-yl]methanone

F053-2916 Screening compound: cyclopropyl[6-(2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-1-ylsulfonyl)-2-methyl-2,3-dihydro-4H-1,4-benzothiazin-4-yl]methanone
F053-2916 Screening compound: cyclopropyl[6-(2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-1-ylsulfonyl)-2-methyl-2,3-dihydro-4H-1,4-benzothiazin-4-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound F053-2916
cyclopropyl[6-(2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-1-ylsulfonyl)-2-methyl-2,3-dihydro-4H-1,4-benzothiazin-4-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F053-2916

Molecular Formula

C22H22N4O3S2 (C22 H22 N4 O3 S2)

Compound Name

cyclopropyl[6-(2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-1-ylsulfonyl)-2-methyl-2,3-dihydro-4H-1,4-benzothiazin-4-yl]methanone

IUPAC name

5-[(4-cyclopropanecarbonyl-2-methyl-34-dihydro-2H-14-benzothiazin-6-yl)sulfonyl]-257-triazatricyclo[6.4.0.0^{26}]dodeca-1(8)6911-tetraene

SMILES

CC(C1)Sc(ccc(S(N2c3nc(cccc4)c4n3CC2)(=O)=O)c2)c2N1C(C1CC1)=O

InChI

InChI=1S/C22H22N4O3S2/c1-14-13-25(21(27)15-6-7-15)19-12-16(8-9-20(19)30-14)31(28,29)26-11-10-24-18-5-3-2-4-17(18)23-22(24)26/h2-5,8-9,12,14-15H,6-7,10-11,13H2,1H3/t14-/m1/s1

InChI Key

OUDYRLFYYRFWHF-CQSZACIVSA-N

MDL Number (MFCD)

MFCD27096746

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.151

Distribution Coefficient, logD

3.515

Water Solubility, LogSw

-4.22

Polar Surface Area

57.454

Acid Dissociation Constant (pKa)

21.34

Base Dissociation Constant (pKb)

7.92

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

F053-2916 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F053-2916 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F053-2916?
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What is the minimum amount of F053-2916 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F053-2916
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F053-2916
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F053-2916 available by request