F067-0518 Screening compound: 2-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-N-(2-methoxyethyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

F067-0518 Screening compound: 2-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-N-(2-methoxyethyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide
F067-0518 Screening compound: 2-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-N-(2-methoxyethyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F067-0518
2-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-N-(2-methoxyethyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F067-0518

Molecular Formula

C29H29N3O5S (C29 H29 N3 O5 S)

Compound Name

2-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-N-(2-methoxyethyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

IUPAC name

2-{[2-(24-dimethylphenyl)-2-oxoethyl]sulfanyl}-N-(2-methoxyethyl)-3-(4-methoxyphenyl)-4-oxo-34-dihydroquinazoline-7-carboxamide

SMILES

Cc(cc1)cc(C)c1C(CSC(N1c(cc2)ccc2OC)=Nc(cc(cc2)C(NCCOC)=O)c2C1=O)=O

InChI

InChI=1S/C29H29N3O5S/c1-18-5-11-23(19(2)15-18)26(33)17-38-29-31-25-16-20(27(34)30-13-14-36-3)6-12-24(25)28(35)32(29)21-7-9-22(37-4)10-8-21/h5-12,15-16H,13-14,17H2,1-4H3,(H,30,34)

InChI Key

UZBGDDZBUFAVAX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14939247

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

531.63

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.114

Distribution Coefficient, logD

4.114

Water Solubility, LogSw

-4.30

Polar Surface Area

78.819

Acid Dissociation Constant (pKa)

12.88

Base Dissociation Constant (pKb)

3.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.10

F067-0518 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with F067-0518 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F067-0518?
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What is the minimum amount of F067-0518 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F067-0518
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F067-0518
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F067-0518 available by request