F067-1138 Screening compound: 3-(3-fluorophenyl)-N-(2-methoxyethyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydroquinazoline-7-carboxamide

F067-1138 Screening compound: 3-(3-fluorophenyl)-N-(2-methoxyethyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydroquinazoline-7-carboxamide
F067-1138 Screening compound: 3-(3-fluorophenyl)-N-(2-methoxyethyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydroquinazoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F067-1138
3-(3-fluorophenyl)-N-(2-methoxyethyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydroquinazoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F067-1138

Molecular Formula

C26H22FN3O4S (C26 H22 FN3 O4 S)

Compound Name

3-(3-fluorophenyl)-N-(2-methoxyethyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydroquinazoline-7-carboxamide

IUPAC name

3-(3-fluorophenyl)-N-(2-methoxyethyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-34-dihydroquinazoline-7-carboxamide

SMILES

COCCNC(c(cc1)cc(N=C(N2c3cc(F)ccc3)SCC(c3ccccc3)=O)c1C2=O)=O

InChI

InChI=1S/C26H22FN3O4S/c1-34-13-12-28-24(32)18-10-11-21-22(14-18)29-26(35-16-23(31)17-6-3-2-4-7-17)30(25(21)33)20-9-5-8-19(27)15-20/h2-11,14-15H,12-13,16H2,1H3,(H,28,32)

InChI Key

WYWXWCXAHSSXIW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14939376

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.983

Distribution Coefficient, logD

2.983

Water Solubility, LogSw

-3.69

Polar Surface Area

71.275

Acid Dissociation Constant (pKa)

12.88

Base Dissociation Constant (pKb)

3.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

F067-1138 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F067-1138 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F067-1138?
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What is the minimum amount of F067-1138 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F067-1138
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F067-1138
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F067-1138 available by request